Multi-functional compound micromachines for targeted therapy
We have fabricated multi-functional compound micromachines in our lab using 3D direct laser writing and selective physical vapour deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism were engineered for spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels. In this project, these mciromachines were engineered to noninvasively collect biological samples from remote pathological sites for diagnostic purposes using magnetic and acoustic actuation.
Contacts: Tianyun Huang, Daniel Ahmed
References:
Huang, Tian‐Yun, et al. "3D printed microtransporters: Compound micromachines for spatiotemporally controlled delivery of therapeutic agents". Advanced Materials 27.42 (2015): 6644-6650.
Huang, Tian-Yun, et al. "Generating mobile fluidic traps for selective three-dimensional transport of microobjects." Applied Physics Letters 105.11 (2014): 114102.